Exercise
Moderate continuous running for cardiorespiratory and mood benefits.[1385,1632,1768, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
45
Positive Lean • confidence Moderate
Safety Friction
88/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 18 • mentions 8 • links 27
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Intensity: moderate.[441,1226,1385, etc.]
Weekly dose: 90-210 min/week.[441,1226,1385, etc.]
Best fit: Users with basic running tolerance and impact capacity..[441,1226,1385, etc.]
Goal alignment: Heart Health, Metabolic Health, Mood, Longevity.[441,1226,1385, etc.]
Training Intensity
Moderate
Evidence Tier
HIGH
Weekly Dose
90-210 min/week
Clinical Depth
Humans: 1,187 • RCTs: 152 • Meta: 28
Cohort / Real-World
Cohort signals: 97
Safety Markers
Adverse signals: 89 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
1187 total studies · 2 recent
Timeline
Total indexed
1,187
Human studies
1,187
Cardiovascular signals
193
Randomized trials
152
Metabolic signals
129
Cohort signals
97
Weighted direction score: 45 (Positive Lean)
High when there are replicated human meta-analyses or substantial human RCT/cohort depth.
Total indexed
1,187
Human studies
1,187
Cardiovascular signals
193
Randomized trials
152
Metabolic signals
129
Cohort signals
97
Safety adverse signals
89
Body-composition signals
57
Neurocognitive signals
34
Meta-analyses
28
In vitro / tissue
5
Distribution of evidence by study design strength
Evidence Strength: High
PMID 38355154 • 2024 Feb 14
Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials.
BMJ
Open PubMedPMID 32350100 • 2020 Jul
Effect of aerobic exercise training on asthma in adults: a systematic review and meta-analysis.
Eur Respir J
Open PubMedPMID 19454641 • 2009 May 20
Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis.
JAMA
Open PubMedBenefit reports: 4
Adverse reports: 1
No-effect reports: 0
Mixed reports: 1
Unclear reports: 2
Signal confidence: 0.52
Benefits
Adverse
No Effect
Community confidence 0.52 with mentions: benefit 2, adverse 0, no-effect 0.
Subreddit coverage: Swimming, cycling, running, sleep.
post • r/running • benefit
Slower runners, how do you stay motivated when/if people mock your pace? I’ve done a HM in 2024 and I basically went from 0 to HM in 6-7 months, I loved my race even though I was slow. I’m now training for a full marathon in April and my p…
Open mentionpost • r/Swimming • benefit
Is there a training regime like in a gym or is this more like jogging when you swim and never stop please? Hi, maybe a silly question. I'm wondering how do you all swim and how does it work? I'm still at the beginning of learning but I won…
Open mentionpost • r/cycling • unclear
Bike Headlight PSA! Edit: this is not an angry trucker rant/vent. I’m not annoyed or complaining. I just want to make sure cyclists are safe as the days start getting darker. And guess what, I’m a bike commuter too! I practise what I preac…
Evidence Sources
PUBMED • Human exercise literature
Counts from structured exercise-focused PubMed query set.
Outcome: Humans 1187, RCT 152, meta 28, cohort 97, cardio signals 193, metabolic signals 129.[1385,1632,1768, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38355154 from BMJ.
Outcome: See linked PubMed abstract for methods and outcomes.[,, etc.]
Best Fit
Users with basic running tolerance and impact capacity.
Animal-only studies
0
Composite of study volume, RCTs, and meta-analyses
PMID 27168471 • 2016 May
Acute Effects of Exercise on Blood Pressure: A Meta-Analytic Investigation.
Arq Bras Cardiol
Open PubMedPMID 31685526 • 2020 Aug
Is running associated with a lower risk of all-cause, cardiovascular and cancer mortality, and is the more the better? A systematic review and meta-analysis.
Br J Sports Med
Open PubMedPMID 26304644 • 2015 Oct
Biomechanical Differences of Foot-Strike Patterns During Running: A Systematic Review With Meta-analysis.
J Orthop Sports Phys Ther
Open PubMedPMID 27379904 • 2016 Aug 1
Effects of Moderate and Vigorous Exercise on Nonalcoholic Fatty Liver Disease: A Randomized Clinical Trial.
JAMA Intern Med
Open PubMedPMID 32130593 • 2020 Nov
Brief Report: Impact of a Physical Exercise Intervention on Emotion Regulation and Behavioral Functioning in Children with Autism Spectrum Disorder.
J Autism Dev Disord
Open PubMedPMID 38368307 • 2024 May
Twelve-month resistance and impact exercise program or risedronate provides a relative benefit to hip bone structure in postmenopausal women: results from a randomized controlled trial.
Osteoporos Int
Open PubMedPMID 1765033 • 1991
Stress reactivity and exercise training in premenopausal and postmenopausal women.
Health Psychol
Open PubMedPMID 37294216 • 2022 Nov-Dec
Effect of Aerobic Exercise on the Levels of Pain, Quality of Life, and Alexithymia in Alexithymic Individuals With Chronic Pain: A Single-Blinded Randomized Controlled Trial.
J Manipulative Physiol Ther
Open PubMedPMID 15699447 • 2005 Mar
Endurance exercise training in orthostatic intolerance: a randomized, controlled trial.
Hypertension
Open PubMedPMID 30193744 • 2018 Dec
Various Leisure-Time Physical Activities Associated With Widely Divergent Life Expectancies: The Copenhagen City Heart Study.
Mayo Clin Proc
Open PubMedPMID 30671455 • 2018
The Effectiveness of Physical Exercise on Bone Density in Osteoporotic Patients.
Biomed Res Int
Open PubMedPMID 33139666 • 2020 Nov 1
A Scoping Review of the Relationship between Running and Mental Health.
Int J Environ Res Public Health
Open PubMedPMID 10919953 • 2000 Aug
Physical activity as a metabolic stressor.
Am J Clin Nutr
Open PubMedPMID 34724167 • 2021 Nov
Exercise Training: The Holistic Approach in Cardiovascular Prevention.
High Blood Press Cardiovasc Prev
Open PubMedPMID 36997475 • 2023 Jul
Additional effects of exercise to hypocaloric diet on body weight, body composition, glycaemic control and cardio-respiratory fitness in adults with overweight or obesity and type 2 diabetes: A systematic review and meta-analysis.
Diabet Med
Open PubMedpost • r/sleep • mixed
Deep sleep almost doubled in 14 months. Breakdown of what I changed. 42M. For most of my 30s I slept 6-7 hours a night and thought that was fine. Tired during the day, wired at night, rarely felt rested. Apple Watch consistently showing 40…
Open mentioncomment • r/running • unclear
A mix of both, two of my friends basically said I’m not running im jogging at that pace or if I take walk breaks during a race I’m not actually running it. Normally I don’t care and I’m very happy with my progress and I’m running to show m…
Open mentionCommunity Sources
PUBMED • 2020 • Human evidence curation set
PMID 32350100 from Eur Respir J.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2009 • Human evidence curation set
PMID 19454641 from JAMA.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 27168471 from Arq Bras Cardiol.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 31685526 from Br J Sports Med.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 26304644 from J Orthop Sports Phys Ther.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 27379904 from JAMA Intern Med.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32130593 from J Autism Dev Disord.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38368307 from Osteoporos Int.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 1991 • Human evidence curation set
PMID 1765033 from Health Psychol.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 37294216 from J Manipulative Physiol Ther.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2005 • Human evidence curation set
PMID 15699447 from Hypertension.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30193744 from Mayo Clin Proc.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30671455 from Biomed Res Int.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 33139666 from Int J Environ Res Public Health.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2000 • Human evidence curation set
PMID 10919953 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34724167 from High Blood Press Cardiovasc Prev.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36997475 from Diabet Med.
Outcome: See linked PubMed abstract for methods and outcomes.[1385,1632,1768, etc.]
Open source