Food
Organosulfur compounds may support lipid and blood-pressure related pathways.[1390,2358,2380, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
45/100
Moderate signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
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Classification: prioritize.[1087,1210,1390, etc.]
Best fit: Users with mild cardiometabolic risk..[1087,1210,1390, etc.]
Goal alignment: Heart Health, Immune Support, Metabolic Health.[1087,1210,1390, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users with mild cardiometabolic risk.
Primary Focus
Heart Health, Immune Support
Clinical Depth
Humans: 108 • RCTs: 70 • Meta: 38
Cohort / Real-World
Cohort signals: 15
Safety Markers
Adverse signals: 9 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
131 total studies · 4 recent
Timeline
Total indexed
131
Human studies
108
Randomized trials
70
Meta-analyses
38
Animal-only studies
29
In vitro / tissue
24
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
131
Human studies
108
Randomized trials
70
Meta-analyses
38
Animal-only studies
29
In vitro / tissue
24
Cohort signals
15
Safety adverse signals
9
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 37033930 • 2023
Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials.
Front Immunol
Open PubMedPMID 39113105 • 2024 Aug 7
Garlic consumption can reduce the risk of dyslipidemia: a meta-analysis of randomized controlled trials.
J Health Popul Nutr
Open PubMedPMID 37481521 • 2023 Jul 22
Effects of garlic supplementation on components of metabolic syndrome: a systematic review, meta-analysis, and meta-regression of randomized controlled trials.
Benefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22garlic%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 108, RCT 70, meta 38, cohort 15.[1390,2358,2380, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37033930 from Front Immunol.
Outcome: See linked PubMed abstract for methods and outcomes.
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
BMC Complement Med Ther
PMID 26693740 • 2015
Garlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials.
Asia Pac J Clin Nutr
Open PubMedPMID 11010950 • 2000 Oct
Garlic consumption and cancer prevention: meta-analyses of colorectal and stomach cancers.
Am J Clin Nutr
Open PubMedPMID 31895803 • 2020 Jan
Garlic intake and the risk of colorectal cancer: A meta-analysis.
Medicine (Baltimore)
Open PubMedPMID 35276764 • 2022 Jan 18
Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study.
Nutrients
Open PubMedPMID 39203947 • 2024 Aug 22
LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers.
Nutrients
Open PubMedPMID 40266024 • 2025 Apr 17
Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study.
Aging (Albany NY)
Open PubMedPMID 36789941 • 2023 Jan
Allium vegetable intake associated with the risk of incident gastric cancer: a continuous follow-up study of a randomized intervention trial.
Am J Clin Nutr
Open PubMedPMID 29937536 • 2018 Jun 24
Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods.
Nutrients
Open PubMedPMID 40770379 • 2025 Aug 6
Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial.
J Health Popul Nutr
Open PubMedPMID 25411831 • 2015
Meta-analysis: Does garlic intake reduce risk of gastric cancer?
Nutr Cancer
Open PubMedPMID 25215621 • 2015 Jan
Allium vegetable intake and gastric cancer: a case-control study and meta-analysis.
Mol Nutr Food Res
Open PubMedPMID 25335850 • 2015 May 15
Dietary supplement use and colorectal cancer risk: a systematic review and meta-analyses of prospective cohort studies.
Int J Cancer
Open PubMedPMID 25386091 • 2014 Nov 7
Consumption of garlic and risk of colorectal cancer: an updated meta-analysis of prospective studies.
World J Gastroenterol
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=garlic
Community Sources
PUBMED • 2024 • Human evidence curation set
PMID 39113105 from J Health Popul Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37481521 from BMC Complement Med Ther.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 26693740 from Asia Pac J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2000 • Human evidence curation set
PMID 11010950 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 31895803 from Medicine (Baltimore).
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35276764 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39203947 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40266024 from Aging (Albany NY).
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36789941 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29937536 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40770379 from J Health Popul Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25411831 from Nutr Cancer.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25215621 from Mol Nutr Food Res.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25335850 from Int J Cancer.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 25386091 from World J Gastroenterol.
Outcome: See linked PubMed abstract for methods and outcomes.[1390,2358,2380, etc.]
Open source