Food
Fungal polysaccharides and ergothioneine-containing foods are linked with antioxidant and immune pathways.[2294,2462,2812, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
31/100
Early signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
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Classification: prioritize.[1108,1246,2294, etc.]
Best fit: Users with low vegetable and mushroom intake..[1108,1246,2294, etc.]
Goal alignment: Immune Support, Metabolic Health, Longevity.[1108,1246,2294, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users with low vegetable and mushroom intake.
Primary Focus
Immune Support, Metabolic Health
Clinical Depth
Humans: 89 • RCTs: 4 • Meta: 4
Cohort / Real-World
Cohort signals: 20
Safety Markers
Adverse signals: 4 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
89 total studies · 1 recent
Timeline
Total indexed
89
Human studies
89
Cohort signals
20
In vitro / tissue
6
Randomized trials
4
Meta-analyses
4
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
89
Human studies
89
Cohort signals
20
In vitro / tissue
6
Randomized trials
4
Meta-analyses
4
Safety adverse signals
4
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
PMID 36912187 • 2023 May 1
Mushroom consumption and risk of gastric cancer: a pooled analysis within the stomach cancer pooling project and a combined meta-analysis with other observational studies.
Eur J Cancer Prev
Open PubMedPMID 33724299 • 2021 Oct 1
Higher Mushroom Consumption Is Associated with Lower Risk of Cancer: A Systematic Review and Meta-Analysis of Observational Studies.
Adv Nutr
Open PubMedPMID 34548082 • 2021 Sep 21
Prospective study of dietary mushroom intake and risk of mortality: results from continuous National Health and Nutrition Examination Survey (NHANES) 2003-2014 and a meta-analysis.
Benefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
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aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 89, RCT 4, meta 4, cohort 20.[2294,2462,2812, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36912187 from Eur J Cancer Prev.
Outcome: See linked PubMed abstract for methods and outcomes.
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Composite of study volume, RCTs, and meta-analyses
Nutr J
PMID 24691133 • 2014
Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies.
PLoS One
Open PubMedPMID 28647383 • 2017 Oct 1
Impact of Agaricus bisporus mushroom consumption on satiety and food intake.
Appetite
Open PubMedPMID 38135005 • 2024 Feb
Consuming Mushrooms When Adopting a Healthy Mediterranean-Style Dietary Pattern Does Not Influence Short-Term Changes of Most Cardiometabolic Disease Risk Factors in Healthy Middle-Aged and Older Adults.
J Nutr
Open PubMedPMID 30279332 • 2018 Oct 2
Impact of Agaricus bisporus Mushroom Consumption on Gut Health Markers in Healthy Adults.
Nutrients
Open PubMedPMID 25866155 • 2015
Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults.
J Am Coll Nutr
Open PubMedPMID 34216974 • 2021 Aug 15
An amyotrophic lateral sclerosis hot spot in the French Alps associated with genotoxic fungi.
J Neurol Sci
Open PubMedPMID 33309597 • 2021 May
Mushroom Consumption and Cardiovascular Health: A Systematic Review.
Am J Med
Open PubMedPMID 37990262 • 2023 Nov 22
Mushroom consumption and hyperuricemia: results from the National Institute for Longevity Sciences-Longitudinal Study of Aging and the National Health and Nutrition Examination Survey (2007-2018).
Nutr J
Open PubMedPMID 34606546 • 2021 Oct 4
Edible mushroom consumption and incident hyperuricemia: results from the TCLSIH cohort study.
Food Funct
Open PubMedPMID 33888143 • 2021 Apr 22
Association of mushroom consumption with all-cause and cause-specific mortality among American adults: prospective cohort study findings from NHANES III.
Nutr J
Open PubMedPMID 33559585 • 2020 Oct 16
Mushroom Poisoning.
Dtsch Arztebl Int
Open PubMedPMID 32630215 • 2020 Jul 1
Breast Cancer Primary Prevention and Diet: An Umbrella Review.
Int J Environ Res Public Health
Open PubMedPMID 30986058 • 2019 May 8
Mushroom Toxins: Chemistry and Toxicology.
J Agric Food Chem
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=mushrooms
Community Sources
PUBMED • 2021 • Human evidence curation set
PMID 33724299 from Adv Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34548082 from Nutr J.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 24691133 from PLoS One.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 28647383 from Appetite.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38135005 from J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30279332 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25866155 from J Am Coll Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34216974 from J Neurol Sci.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33309597 from Am J Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37990262 from Nutr J.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34606546 from Food Funct.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33888143 from Nutr J.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 33559585 from Dtsch Arztebl Int.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32630215 from Int J Environ Res Public Health.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30986058 from J Agric Food Chem.
Outcome: See linked PubMed abstract for methods and outcomes.[2294,2462,2812, etc.]
Open source