Food
Isoflavone-containing foods can support lipid and menopausal-symptom endpoints in subsets.[2977,3166,3167, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
96/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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Classification: case-dependent.[1132,1283,2977, etc.]
Best fit: Users replacing processed meat with plant protein..[1132,1283,2977, etc.]
Goal alignment: Heart Health, Hormone Health, Bone Health.[1132,1283,2977, etc.]
Classification
Case Dependent
Evidence Tier
HIGH
Best Fit
Users replacing processed meat with plant protein.
Primary Focus
Heart Health, Hormone Health
Clinical Depth
Humans: 3,338 • RCTs: 623 • Meta: 154
Cohort / Real-World
Cohort signals: 407
Safety Markers
Adverse signals: 137 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
↑ Growing evidence base
Depth
3338 total studies · 2 recent
Timeline
Total indexed
3,338
Human studies
3,338
Randomized trials
623
In vitro / tissue
573
Cohort signals
407
Meta-analyses
154
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
3,338
Human studies
3,338
Randomized trials
623
In vitro / tissue
573
Cohort signals
407
Meta-analyses
154
Safety adverse signals
137
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
PMID 33383165 • 2021 Mar
Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies.
Reprod Toxicol
Open PubMedPMID 35241506 • 2022 Mar-Apr
Soy Isoflavones and Breast Cancer Risk: A Meta-analysis.
In Vivo
Open PubMedPMID 34348965 • 2021 Aug 4
Effect of low glycaemic index or load dietary patterns on glycaemic control and cardiometabolic risk factors in diabetes: systematic review and meta-analysis of randomised controlled trials.
BMJ
Benefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22soy%20foods%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 3338, RCT 623, meta 154, cohort 407.[2977,3166,3167, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33383165 from Reprod Toxicol.
Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Composite of study volume, RCTs, and meta-analyses
PMID 30485934 • 2018
Dietary factors and risk of gout and hyperuricemia: a meta-analysis and systematic review.
Asia Pac J Clin Nutr
Open PubMedPMID 40533200 • 2025 Jun 18
Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials.
BMJ
Open PubMedPMID 33762150 • 2021 May 6
The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials.
Nutr Metab Cardiovasc Dis
Open PubMedPMID 29562612 • 2018 Mar 17
Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder-A Randomized, Controlled 12-Month Trial.
Nutrients
Open PubMedPMID 34358827 • 2021 Aug
Supplement-based nutritional strategies to tackle frailty: A multifactorial, double-blind, randomized placebo-controlled trial.
Clin Nutr
Open PubMedPMID 39275135 • 2024 Aug 23
The Portfolio Diet and HbA1c in Adults Living with Type 2 Diabetes Mellitus: A Patient-Level Pooled Analysis of Two Randomized Dietary Trials.
Nutrients
Open PubMedPMID 33726784 • 2021 Mar 16
Effect of whey vs. soy protein supplementation on recovery kinetics following speed endurance training in competitive male soccer players: a randomized controlled trial.
J Int Soc Sports Nutr
Open PubMedPMID 35105389 • 2022 Oct 28
The plasma amino acid response to blended protein beverages: a randomised crossover trial.
Br J Nutr
Open PubMedPMID 30485922 • 2018
Acute effect of soy and soy products on serum uric acid concentration among healthy Chinese men.
Asia Pac J Clin Nutr
Open PubMedPMID 32095830 • 2020 Oct 1
Dairy, soy, and risk of breast cancer: those confounded milks.
Int J Epidemiol
Open PubMedPMID 30742825 • 2019 Jun
Dietary patterns and outcomes of assisted reproduction.
Am J Obstet Gynecol
Open PubMedPMID 37877288 • 2023 Nov 28
Portfolio Diet Score and Risk of Cardiovascular Disease: Findings From 3 Prospective Cohort Studies.
Circulation
Open PubMedPMID 36162007 • 2023 Jan 1
The Portfolio Diet and Incident Type 2 Diabetes: Findings From the Women's Health Initiative Prospective Cohort Study.
Diabetes Care
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=soy%20foods
Community Sources
PUBMED • 2022 • Human evidence curation set
PMID 35241506 from In Vivo.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34348965 from BMJ.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30485934 from Asia Pac J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40533200 from BMJ.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33762150 from Nutr Metab Cardiovasc Dis.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29562612 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34358827 from Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39275135 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33726784 from J Int Soc Sports Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35105389 from Br J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30485922 from Asia Pac J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32095830 from Int J Epidemiol.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30742825 from Am J Obstet Gynecol.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37877288 from Circulation.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36162007 from Diabetes Care.
Outcome: See linked PubMed abstract for methods and outcomes.[2977,3166,3167, etc.]
Open source