Food
Protein-rich cyanobacterial food source with antioxidant-related compounds.[2070,2409,2494, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
67/100
Moderate signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
Classification: prioritize.[1133,1284,2070, etc.]
Best fit: Users expanding nutrient diversity where quality-tested products are used..[1133,1284,2070, etc.]
Goal alignment: Metabolic Health, Immune Support, Recovery.[1133,1284,2070, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users expanding nutrient diversity where quality-tested products are used.
Primary Focus
Metabolic Health, Immune Support
Clinical Depth
Humans: 254 • RCTs: 44 • Meta: 10
Cohort / Real-World
Cohort signals: 6
Safety Markers
Adverse signals: 30 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
254 total studies · 4 recent
Timeline
Total indexed
254
Human studies
254
In vitro / tissue
158
Randomized trials
44
Safety adverse signals
30
Meta-analyses
10
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
254
Human studies
254
In vitro / tissue
158
Randomized trials
44
Safety adverse signals
30
Meta-analyses
10
Cohort signals
6
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
PMID 37097415 • 2023 Jun
Acute and Chronic Performance Enhancement in Rowing: A Network Meta-analytical Approach on the Effects of Nutrition and Training.
Sports Med
Open PubMedPMID 33908048 • 2021 Aug
Spirulina supplementation and oxidative stress and pro-inflammatory biomarkers: A systematic review and meta-analysis of controlled clinical trials.
Clin Exp Pharmacol Physiol
Open PubMedPMID 34235823 • 2021 Oct
Spirulina supplementation as an adjuvant therapy in enhancement of antioxidant capacity: A systematic review and meta-analysis of controlled clinical trials.
Benefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
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aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 254, RCT 44, meta 10, cohort 6.[2070,2409,2494, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37097415 from Sports Med.
Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Composite of study volume, RCTs, and meta-analyses
Int J Clin Pract
PMID 40953712 • 2025 Nov
Spirulina's impacts on cardiovascular health: Insights from a systematic meta-analysis of RCT.
Complement Ther Med
Open PubMedPMID 34496677 • 2021 Jan-Dec
Complementary and Alternative Therapies for Weight Loss: A Narrative Review.
J Evid Based Integr Med
Open PubMedPMID 40289965 • 2025 Mar 7
The Role of Chlorella and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Nutrients
Open PubMedPMID 40877830 • 2025 Aug 28
Effects of spirulina (Arthrospira) platensis supplementation on inflammation, physical and mental quality of life, and anthropometric measures in patients with relapsing-remitting multiple sclerosis (RRMS): a triple-blinded, randomized, placebo-controlled trial.
Nutr J
Open PubMedPMID 36861852 • 2023 Jul
The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double-blind, controlled trial.
Phytother Res
Open PubMedPMID 37739734 • 2023 Oct
The effects of spirulina supplementation on serum iron and ferritin, anemia parameters, and fecal occult blood in adults with ulcerative colitis: A randomized, double-blinded, placebo-controlled trial.
Clin Nutr ESPEN
Open PubMedPMID 36476193 • 2022 Dec 7
Spirulina as a daily nutritional supplement of young pre-school Cambodian children of deprived settings: a single-blinded, placebo-controlled, cross-over trial.
BMC Pediatr
Open PubMedPMID 27880079 • 2017 Feb 1
Relationship Between Gastric Emptying and Diurnal Glycemic Control in Type 1 Diabetes Mellitus: A Randomized Trial.
J Clin Endocrinol Metab
Open PubMedPMID 38401078 • 2024 Feb
Spirulina Platensis Attenuates Rebound Dyspeptic Symptoms After Proton Pump Inhibitors' Discontinuation: Phase 2 Placebo-controlled Trial.
Altern Ther Health Med
Open PubMedPMID 27914909 • 2017 Apr
Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology.
Eur Ann Otorhinolaryngol Head Neck Dis
Open PubMedPMID 25496727 • 2014 Dec 13
Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study.
Lipids Health Dis
Open PubMedPMID 26195001 • 2015 Jul 21
Impact of daily supplementation of Spirulina platensis on the immune system of naïve HIV-1 patients in Cameroon: a 12-months single blind, randomized, multicenter trial.
Nutr J
Open PubMedPMID 22001128 • 2012 Jan
Minimizing the cancer-promotional activity of cox-2 as a central strategy in cancer prevention.
Med Hypotheses
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=spirulina
Community Sources
PUBMED • 2021 • Human evidence curation set
PMID 33908048 from Clin Exp Pharmacol Physiol.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34235823 from Int J Clin Pract.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40953712 from Complement Ther Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34496677 from J Evid Based Integr Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40289965 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40877830 from Nutr J.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36861852 from Phytother Res.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37739734 from Clin Nutr ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36476193 from BMC Pediatr.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 27880079 from J Clin Endocrinol Metab.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38401078 from Altern Ther Health Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 27914909 from Eur Ann Otorhinolaryngol Head Neck Dis.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 25496727 from Lipids Health Dis.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 26195001 from Nutr J.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open sourcePUBMED • 2012 • Human evidence curation set
PMID 22001128 from Med Hypotheses.
Outcome: See linked PubMed abstract for methods and outcomes.[2070,2409,2494, etc.]
Open source