Food
Beta-glucan fibers support LDL lowering and improved glycemic dynamics.[2029,2345,2348, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
31/100
Early signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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Classification: prioritize.[1149,1309,2029, etc.]
Best fit: Users with elevated LDL and low soluble-fiber intake..[1149,1309,2029, etc.]
Goal alignment: Heart Health, Metabolic Health, Gut Health.[1149,1309,2029, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users with elevated LDL and low soluble-fiber intake.
Primary Focus
Heart Health, Metabolic Health
Clinical Depth
Humans: 200 • RCTs: 64 • Meta: 17
Cohort / Real-World
Cohort signals: 3
Safety Markers
Adverse signals: 4 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
200 total studies · 2 recent
Timeline
Total indexed
200
Human studies
200
Randomized trials
64
In vitro / tissue
59
Meta-analyses
17
Safety adverse signals
4
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
200
Human studies
200
Randomized trials
64
In vitro / tissue
59
Meta-analyses
17
Safety adverse signals
4
Cohort signals
3
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 27724985 • 2016 Oct
The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: a systematic review and meta-analysis of randomised-controlled trials.
Br J Nutr
Open PubMedPMID 26001090 • 2015
A systematic review and meta-analysis of beta-glucan consumption on glycemic control in hypercholesterolemic individuals.
Int J Food Sci Nutr
Open PubMedPMID 36657917 • 2023 Feb
The separate effects of whole oats and isolated beta-glucan on lipid profile: A systematic review and meta-analysis of randomized controlled trials.
Benefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 200, RCT 64, meta 17, cohort 3.[2029,2345,2348, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 27724985 from Br J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Clin Nutr ESPEN
PMID 25411276 • 2014 Dec
Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials.
Am J Clin Nutr
Open PubMedPMID 21470820 • 2011 Oct
Meta-analysis of the effect of β-glucan intake on blood cholesterol and glucose levels.
Nutrition
Open PubMedPMID 26840185 • 2016 Mar
The difference between oats and beta-glucan extract intake in the management of HbA1c, fasting glucose and insulin sensitivity: a meta-analysis of randomized controlled trials.
Food Funct
Open PubMedPMID 34956218 • 2021
The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial.
Front Immunol
Open PubMedPMID 31828287 • 2020 Feb 1
Increasing oat β-glucan viscosity in a breakfast meal slows gastric emptying and reduces glycemic and insulinemic responses but has no effect on appetite, food intake, or plasma ghrelin and PYY responses in healthy humans: a randomized, placebo-controlled, crossover trial.
Am J Clin Nutr
Open PubMedPMID 36124913 • 2022 Oct 3
Effects of whole-grain barley and oat β-glucans on postprandial glycemia and appetite: a randomized controlled crossover trial.
Food Funct
Open PubMedPMID 39599684 • 2024 Nov 15
Effect of Barley on Postprandial Blood Glucose Response and Appetite in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial.
Nutrients
Open PubMedPMID 29115200 • 2017 Nov
Barley β-glucan reduces blood cholesterol levels via interrupting bile acid metabolism.
Br J Nutr
Open PubMedPMID 41031804 • 2025 Jan 1
Effect of oat β-glucan in managing blood pressure: a randomized cross-over pilot trial.
Appl Physiol Nutr Metab
Open PubMedPMID 25106092 • 2014 Dec
Molecular weight of barley β-glucan does not influence satiety or energy intake in healthy male subjects.
Appetite
Open PubMedPMID 25139426 • 2014 Dec
Effect of cooked white rice with high β-glucan barley on appetite and energy intake in healthy Japanese subjects: a randomized controlled trial.
Plant Foods Hum Nutr
Open PubMedPMID 26273900 • 2016
Instant Oatmeal Increases Satiety and Reduces Energy Intake Compared to a Ready-to-Eat Oat-Based Breakfast Cereal: A Randomized Crossover Trial.
J Am Coll Nutr
Open PubMedPMID 31960663 • 2019
Nutraceutical functions of beta-glucans in human nutrition.
Rocz Panstw Zakl Hig
Open PubMedCommunity Sources
PUBMED • 2015 • Human evidence curation set
PMID 26001090 from Int J Food Sci Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36657917 from Clin Nutr ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 25411276 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2011 • Human evidence curation set
PMID 21470820 from Nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 26840185 from Food Funct.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34956218 from Front Immunol.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 31828287 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36124913 from Food Funct.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39599684 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 29115200 from Br J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 41031804 from Appl Physiol Nutr Metab.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 25106092 from Appetite.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 25139426 from Plant Foods Hum Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 26273900 from J Am Coll Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31960663 from Rocz Panstw Zakl Hig.
Outcome: See linked PubMed abstract for methods and outcomes.[2029,2345,2348, etc.]
Open source