Habit
Set cutoff for caffeine intake to reduce sleep-latency and fragmentation risk.[1843,1894,1959, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
97/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 24 • mentions 0 • links 35
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Classification: add.[1103,1235,1843, etc.]
Best fit: Users with insomnia, anxiety, or fragmented sleep..[1103,1235,1843, etc.]
Goal alignment: Sleep, Mood, Stress Resilience, Energy.[1103,1235,1843, etc.]
Classification
Add
Evidence Tier
MEDIUM
Best Fit
Users with insomnia, anxiety, or fragmented sleep.
Primary Focus
Sleep, Mood
Clinical Depth
Humans: 309 • RCTs: 22 • Meta: 1
Cohort / Real-World
Cohort signals: 40
Safety Markers
Adverse signals: 16 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
309 total studies · 3 recent
Timeline
Total indexed
309
Human studies
309
Sleep signals
285
Neuropsych signals
101
Cohort signals
40
Cardiometabolic signals
32
Weighted direction score: 0 (Mixed / Neutral)
High when replicated human meta-analysis/trial/cohort depth is present for the habit or exposure.
Total indexed
309
Human studies
309
Sleep signals
285
Neuropsych signals
101
Cohort signals
40
Cardiometabolic signals
32
Randomized trials
22
Safety adverse signals
16
Dependency signals
14
In vitro / tissue
4
Meta-analyses
1
Distribution of evidence by study design strength
Evidence Strength: High
PMID 39103929 • 2024 Aug 5
Effects of caffeine intake on pupillary parameters in humans: a systematic review and meta-analysis.
Behavioral and brain functions : BBF
Open PubMedPMID 39213264 • 2024
Effect of matcha green tea on cognitive functions and sleep quality in older adults with cognitive decline: A randomized controlled study over 12 months.
PloS one
Open PubMedPMID 26378246 • 2015 Sep 16
Effects of caffeine on the human circadian clock in vivo and in vitro.
Science translational medicine
Open PubMedBenefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Human lifestyle/habit literature
Counts from structured habit/exposure PubMed query set.
Outcome: Humans 25, RCT 3, meta 1, cohort 3, sleep signals 23, cardiometabolic signals 1.[1843,1894,1959, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39103929 from Behavioral and brain functions : BBF.
Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Animal-only studies
0
Composite of study volume, RCTs, and meta-analyses
PMID 31202686 • 2019 Aug
Resetting the late timing of 'night owls' has a positive impact on mental health and performance.
Sleep medicine
Open PubMedPMID 40145446 • 2025 Mar-Apr
Caffeine and Beetroot Juice Optimize 1,000-m Performance: Shapley Additive Explanations Analysis.
American journal of men's health
Open PubMedPMID 31398441 • 2019 Oct 15
Cardiac autonomic activity during sleep deprivation with and without caffeine administration.
Physiology & behavior
Open PubMedPMID 27044596 • 2016 Apr 4
Does caffeine reduce postoperative bowel paralysis after elective laparoscopic colectomy? (CaCo trial): study protocol for a randomized controlled trial.
Trials
Open PubMedPMID 33883478 • 2022 Mar-Apr 01
Alcohol and Breast Cancer: Results From the Women's Wellness After Cancer Program Randomized Controlled Trial.
Cancer nursing
Open PubMedPMID 9042530 • 1997 Jan 30
Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans.
Brain research
Open PubMedPMID 18785355 • 2008 Sep
Restoration of risk-propensity during sleep deprivation: caffeine, dextroamphetamine, and modafinil.
Aviation, space, and environmental medicine
Open PubMedPMID 36653409 • 2023 Jan 18
Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a randomized double-blind placebo-controlled trial.
Scientific reports
Open PubMedPMID 25687152 • 2015 Mar
A school-based sleep education program for adolescents: a cluster randomized trial.
Pediatrics
Open PubMedPMID 35363563 • 2022 Jun
The Impact of Caffeine Intake on Mental Health Symptoms in Postmenopausal Females with Overactive Bladder Symptoms: A Randomized, Double-Blind, Placebo-Controlled Trial.
Journal of women's health (2002)
Open PubMedPMID 12424548 • 2002 Nov
Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
Psychopharmacology
Open PubMedPMID 34775507 • 2022 Feb 1
Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation: The I-STOP-AFib Randomized Clinical Trial.
JAMA cardiology
Open PubMedPMID 23094031 • 2012
In-car nocturnal blue light exposure improves motorway driving: a randomized controlled trial.
PloS one
Open PubMedPMID 28885372 • 2017 Sep
Light therapy for multiple sclerosis-associated fatigue: Study protocol for a randomized controlled trial.
Medicine
Open PubMedPMID 20946437 • 2011 Sep
Caffeine protects against increased risk-taking propensity during severe sleep deprivation.
Journal of sleep research
Open PubMedPMID 24611526 • 2014 Nov
Building a self-regulatory model of sleep deprivation and deception: the role of caffeine and social influence.
The Journal of applied psychology
Open PubMedPMID 17765011 • 2008 Jul
Sleep deprivation reduces perceived emotional intelligence and constructive thinking skills.
Sleep medicine
Open PubMedPMID 32933332 • 2020 Sep-Oct
TNFα G308A genotype, resilience to sleep deprivation, and the effect of caffeine on psychomotor vigilance performance in a randomized, double-blind, placebo-controlled, crossover study.
Chronobiology international
Open PubMedPMID 35504555 • 2022 Jul
Modafinil ameliorates the decline in pronunciation-related working memory caused by 36-h acute total sleep deprivation: An ERP study.
Neurobiology of learning and memory
Open PubMedPMID 10088991 • 1999 Jan
Effects of discontinuing coffee intake on iron deficient Guatemalan toddlers' cognitive development and sleep.
Early human development
Open PubMedPMID 36841492 • 2023 Mar-Apr
Sleep physiology, pathophysiology, and sleep hygiene.
Progress in cardiovascular diseases
Open PubMedCommunity Sources
PUBMED • 2015 • Human evidence curation set
PMID 26378246 from Science translational medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31202686 from Sleep medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39213264 from PloS one.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40145446 from American journal of men's health.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31398441 from Physiology & behavior.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 27044596 from Trials.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 33883478 from Cancer nursing.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 1997 • Human evidence curation set
PMID 9042530 from Brain research.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2008 • Human evidence curation set
PMID 18785355 from Aviation, space, and environmental medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36653409 from Scientific reports.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25687152 from Pediatrics.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35363563 from Journal of women's health (2002).
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2002 • Human evidence curation set
PMID 12424548 from Psychopharmacology.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 34775507 from JAMA cardiology.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2012 • Human evidence curation set
PMID 23094031 from PloS one.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 28885372 from Medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2011 • Human evidence curation set
PMID 20946437 from Journal of sleep research.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 24611526 from The Journal of applied psychology.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2008 • Human evidence curation set
PMID 17765011 from Sleep medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32933332 from Chronobiology international.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35504555 from Neurobiology of learning and memory.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 1999 • Human evidence curation set
PMID 10088991 from Early human development.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36841492 from Progress in cardiovascular diseases.
Outcome: See linked PubMed abstract for methods and outcomes.[1843,1894,1959, etc.]
Open source