Habit
Eliminate cigarette smoking due to strong dose-dependent disease burden.[1335,1457,1492, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 24 • mentions 0 • links 35
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Classification: reduce.[1117,1262,1335, etc.]
Best fit: All current smokers..[1117,1262,1335, etc.]
Goal alignment: Longevity, Heart Health, Performance, Immune Support, Liver Support.[1117,1262,1335, etc.]
Classification
Reduce
Evidence Tier
HIGH
Best Fit
All current smokers.
Primary Focus
Longevity, Heart Health
Clinical Depth
Humans: 9,805 • RCTs: 352 • Meta: 131
Cohort / Real-World
Cohort signals: 1,777
Safety Markers
Adverse signals: 474 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
9805 total studies · 2 recent
Timeline
Total indexed
9,805
Human studies
9,805
Cohort signals
1,777
Cardiometabolic signals
1,325
In vitro / tissue
837
Dependency signals
678
Weighted direction score: 0 (Mixed / Neutral)
High when replicated human meta-analysis/trial/cohort depth is present for the habit or exposure.
Total indexed
9,805
Human studies
9,805
Cohort signals
1,777
Cardiometabolic signals
1,325
In vitro / tissue
837
Dependency signals
678
Neuropsych signals
582
Safety adverse signals
474
Randomized trials
352
Sleep signals
165
Meta-analyses
131
Distribution of evidence by study design strength
Evidence Strength: High
PMID 27651444 • 2016 Oct
Epigenetic Signatures of Cigarette Smoking.
Circulation. Cardiovascular genetics
Open PubMedPMID 28471964 • 2017 May
Prenatal, perinatal, and postnatal factors associated with autism: A meta-analysis.
Medicine
Open PubMedPMID 31904248 • 2020 Apr
Self-regulation in childhood as a predictor of future outcomes: A meta-analytic review.
Psychological bulletin
Open PubMedBenefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22quit%20smoking%22%20(exercise%20OR%20training%20OR%20sleep%20OR%20habit%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3AFitness%20OR%20subreddit%3Abodyweightfitness%20OR%20subreddit%3Aweightroom%20OR%20subreddit%3Arunning%20OR%20subreddit%3ACycling%20OR%20subreddit%3Aswimming%20OR%20subreddit%3AHIIT%20OR%20subreddit%3Ayoga%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity%20OR%20subreddit%3Ameditation%20OR%20subreddit%3Asleep%20OR%20subreddit%3Astopsmoking%20OR%20subreddit%3Astopdrinking%20OR%20subreddit%3Aleaves%20OR%20subreddit%3Adecaf%20OR%20subreddit%3Adecidingtobebetter)
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Human lifestyle/habit literature
Counts from structured habit/exposure PubMed query set.
Outcome: Humans 9801, RCT 352, meta 131, cohort 1775, sleep signals 165, cardiometabolic signals 1325.[1335,1457,1492, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 31904248 from Psychological bulletin.
Outcome: See linked PubMed abstract for methods and outcomes.[,, etc.]
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Animal-only studies
0
Composite of study volume, RCTs, and meta-analyses
PMID 35816897 • 2022 Aug
Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies.
EBioMedicine
Open PubMedPMID 34698654 • 2021 Jul 20
Factors for the Primary Prevention of Breast Cancer: A Meta-Analysis of Prospective Cohort Studies.
Journal of research in health sciences
Open PubMedPMID 33418132 • 2022 Mar
Obesity, Type 2 Diabetes, Lifestyle Factors, and Risk of Gallstone Disease: A Mendelian Randomization Investigation.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Open PubMedPMID 40010935 • 2025 Jun 13
Cardiovascular health effects of vaping e-cigarettes: a systematic review and meta-analysis.
Heart (British Cardiac Society)
Open PubMedPMID 32892156 • 2021 Jan
Combined lifestyle factors, all-cause mortality and cardiovascular disease: a systematic review and meta-analysis of prospective cohort studies.
Journal of epidemiology and community health
Open PubMedPMID 37486023 • 2023 Oct
Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor.
Annals of neurology
Open PubMedPMID 26776875 • 2016 Feb
E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis.
The Lancet. Respiratory medicine
Open PubMedPMID 35332429 • 2022 Jun
Cigarette smoking and risk of bladder cancer: a dose-response meta-analysis.
International urology and nephrology
Open PubMedPMID 29519934 • 2019 Jan
Tobacco outlet density and adolescents' cigarette smoking: a meta-analysis.
Tobacco control
Open PubMedPMID 39228169 • 2024 Nov
Tobacco retail availability and smoking-A systematic review and meta-analysis.
Drug and alcohol review
Open PubMedPMID 24594022 • 2014 Mar 5
Cigarette smoking and risk of rheumatoid arthritis: a dose-response meta-analysis.
Arthritis research & therapy
Open PubMedPMID 36426864 • 2023 Apr 6
Exposure to Electronic Cigarette Advertisements and Use of Electronic Cigarettes: A Meta-analysis of Prospective Studies.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Open PubMedPMID 35430427 • 2022 Jun
Cigarette smoking and risk of second primary cancer: a systematic review and meta-analysis.
Cancer epidemiology
Open PubMedPMID 11696868 • 2001 Nov
Lung cancer and type of cigarette smoked.
Inhalation toxicology
Open PubMedPMID 29523476 • 2018 Apr
Health-Related Lifestyle Factors and Sexual Dysfunction: A Meta-Analysis of Population-Based Research.
The journal of sexual medicine
Open PubMedPMID 34988969 • 2022 Jan 6
Heated tobacco products for smoking cessation and reducing smoking prevalence.
The Cochrane database of systematic reviews
Open PubMedPMID 30402966 • 2019 Jun
Maternal smoking during pregnancy and the risk of strabismus in offspring: a meta-analysis.
Acta ophthalmologica
Open PubMedPMID 33588570 • 2021 Jan 1
A Comprehensive Systematic Review and Meta-analysis on the Risk Factors of Stroke in Iranian Population.
Archives of Iranian medicine
Open PubMedPMID 21249154 • 2011 Jan 13
Smoking and multiple sclerosis: an updated meta-analysis.
PloS one
Open PubMedPMID 33782474 • 2021 Mar 29
Systematic review and meta-analysis of female lifestyle factors and risk of recurrent pregnancy loss.
Scientific reports
Open PubMedPMID 9167070 • 1997 May
Maternal cigarette smoking and oral clefts: a meta-analysis.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=quit%20smoking
Community Sources
PUBMED • 2022 • Human evidence curation set
PMID 35816897 from EBioMedicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 28471964 from Medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 27651444 from Circulation. Cardiovascular genetics.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34698654 from Journal of research in health sciences.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 33418132 from Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40010935 from Heart (British Cardiac Society).
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 32892156 from Journal of epidemiology and community health.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37486023 from Annals of neurology.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 26776875 from The Lancet. Respiratory medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35332429 from International urology and nephrology.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 29519934 from Tobacco control.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39228169 from Drug and alcohol review.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 24594022 from Arthritis research & therapy.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36426864 from Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35430427 from Cancer epidemiology.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2001 • Human evidence curation set
PMID 11696868 from Inhalation toxicology.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29523476 from The journal of sexual medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 34988969 from The Cochrane database of systematic reviews.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30402966 from Acta ophthalmologica.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33588570 from Archives of Iranian medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2011 • Human evidence curation set
PMID 21249154 from PloS one.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33782474 from Scientific reports.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open sourcePUBMED • 1997 • Human evidence curation set
PMID 9167070 from The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.
Outcome: See linked PubMed abstract for methods and outcomes.[1335,1457,1492, etc.]
Open source