Session check

Supplement

Ginger Extract (Zingiber officinale)

Gingerols and shogaols inhibit COX-2 and 5-LOX pathways, enhance gastric motility, reduce TNF-α/IL-6, and modulate serotonin receptors to prevent nausea.[1443,1458,1639, etc.]

Superscript reference numbers link to the Sources bibliography.

Strong Evidence

Gut HealthInflammationPain ManagementImmune Supportalias: ginger rootalias: gingerolalias: ginger supplement

Composite Rating

4.7/5

Blends evidence depth, community direction, safety friction, and completeness.

Evidence Intensity

100/100

High depth from human/RCT/meta counts

Community Direction

Positive Lean • confidence Moderate

Safety Friction

0/100

Sparse signal from adverse/interaction markers

Data Completeness

100%

Studies 24 • mentions 7 • links 206

Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.

FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.

If you are experiencing a medical emergency, call 911 or your local emergency number immediately.

Implementation Blueprint

Goal alignment: Gut Health, Inflammation, Pain Management, Immune Support.[1443,1458,1639, etc.]

Dose guide: Human-study daily dose: 84 mg-1200 mg/day (higher-confidence extraction from PubMed abstracts)..[1443,1458,1639, etc.]

Category: botanical.[1443,1458,1639, etc.]

At-A-Glance Evidence Architecture[1443,1458,1639, etc.]

Clinical Depth

Humans: 4 • RCTs: 89 • Meta: 53

Cohort / Real-World

Cohort signals: 11

Safety Markers

Adverse signals: 0 • Interactions: 0

Evidence Tracking

Freshness, trend, and study timeline for this item

Evidence Tracking

Status

New Evidence

Trend

→ Stable evidence base

Depth

204 total studies · 54 recent

Timeline

19902026

Top Signal Metrics[1443,1458,1639, etc.]

Total indexed

204

Randomized trials

Meta-analyses

Cohort signals

Human studies

Mechanistic signals

Community Direction Mix[6172]

Weighted direction score: 24 (Positive Lean)

Benefit4 (57%)

Evidence Quality Summary[1443,1458,1639, etc.]

Total indexed

204

Randomized trials

Meta-analyses

Cohort signals

Human studies

Mechanistic signals

Study Type Breakdown

Distribution of evidence by study design strength

Meta-AnalysesLevel 1a53

Randomized TrialsLevel 1b89

Cohort StudiesLevel 2b11

All IndexedAll levels204

100

Evidence Strength: High

Composite of study volume, RCTs, and meta-analyses

Top Human Studies[1443,1458,1639, etc.]

PMID 25230975 • 2015

Ginger for nausea and vomiting in pregnancy: Cochrane review

META_ANALYSIS

Open PubMed

PMID 25029748 • 2015

Ginger and osteoarthritis pain: MA of 5 RCTs

META_ANALYSIS

Open PubMed

PMID 31174214 • 2019

Ginger and inflammatory markers: MA of RCTs

META_ANALYSIS

Open PubMed

Community Report Frequency[6172]

Benefit reports: 4

Adverse reports: 2

No-effect reports: 0

Mixed reports: 1

Unclear reports: 0

Signal confidence: 0.60

Top Reported Effects[6172]

Benefits

Anti-nausea (pregnancy, chemotherapy, motion sickness): 1
Anti-inflammatory: 1
Pain reduction: 1
Digestive support: 1
Blood sugar regulation: 1

Adverse

Gallbladder obstruction: 1

No Effect

insufficient no-effect reports captured: 0

One of the safest and most versatile herbal supplements. Excellent for nausea (pregnancy-safe) and joint support. | Step2: Insufficient empirical signal for a directional adjustment.

Imported legacy community score: 8.0/10 (heuristic mapping confidence 0.92).

Legacy community note: Universally appreciated for nausea and digestive comfort. Pregnant women rely on it. Anti-inflammatory benefits well-recognized. Fresh ginger in cooking also valued.

Community Evidence Examples[6172]

aggregate • benefit

Aggregate community signal: 7 directional mentions (benefit 4, adverse 2, no-effect 0, mixed 1).

Open mention

Retail Signal Examples

amazon

Amazon search for Ginger Extract (Zingiber officinale)

Rating: n/a | Reviews: n/a

Open product

Primary Source Links

Evidence Sources

Scientific Evidence Notes[1443,1458,1639, etc.]

1. Ginger for nausea and vomiting in pregnancy: Cochrane review

PUBMED • 2015 • Human evidence curation set

PMID 25230975 from META_ANALYSIS.

Outcome: See linked PubMed abstract for methods and outcomes.[1443,1458,1639, etc.]

Open source

2. Ginger and osteoarthritis pain: MA of 5 RCTs

PUBMED • 2015 • Human evidence curation set

PMID 25029748 from META_ANALYSIS.

Outcome: See linked PubMed abstract for methods and outcomes.[1443,1458,1639, etc.]

Open source

Implementation Blueprint

At-A-Glance Evidence Architecture[1443,1458,1639, etc.]

Evidence Tracking

Evidence Tracking

Top Signal Metrics[1443,1458,1639, etc.]

Community Direction Mix[6172]

Evidence Quality Summary[1443,1458,1639, etc.]

Study Type Breakdown

Top Human Studies[1443,1458,1639, etc.]

Community Report Frequency[6172]

Top Reported Effects[6172]

Community Evidence Examples[6172]

Retail Signal Examples

Primary Source Links

Scientific Evidence Notes[1443,1458,1639, etc.]

Safety and Pitfalls