Session check

Supplement

Reishi

Contains bioactive phytochemicals that may modulate stress, immune, and metabolic pathways.[1560,1762,1794, etc.]

Superscript reference numbers link to the Sources bibliography.

Strong Evidence

Stress ResilienceMoodImmune SupportLongevity

Composite Rating

3.4/5

Blends evidence depth, community direction, safety friction, and completeness.

Evidence Intensity

87/100

High depth from human/RCT/meta counts

Community Direction

Mixed / Neutral • confidence Minimal

Safety Friction

100/100

High signal from adverse/interaction markers

Data Completeness

100%

Studies 12 • mentions 4 • links 22

Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.

FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.

If you are experiencing a medical emergency, call 911 or your local emergency number immediately.

Implementation Blueprint

Goal alignment: Stress Resilience, Mood, Immune Support, Longevity.[616,759,991, etc.]

Dose guide: Human-study daily dose: 500 mg-1000 mg/day (higher-confidence extraction from PubMed abstracts)..[616,759,991, etc.]

Category: botanical.[616,759,991, etc.]

At-A-Glance Evidence Architecture[1560,1762,1794, etc.]

Clinical Depth

Humans: 80 • RCTs: 9 • Meta: 0

Cohort / Real-World

Cohort signals: 0

Safety Markers

Adverse signals: 131 • Interactions: 89

Evidence Tracking

Freshness, trend, and study timeline for this item

Evidence Tracking

Status

New Evidence

Trend

→ Stable evidence base

Depth

221 total studies · 2 recent

Timeline

20042024

Top Signal Metrics[1560,1762,1794, etc.]

Animal-only studies

503

In vitro / tissue

317

Total indexed

221

Safety adverse signals

131

Interaction signals

Human studies

Community Direction Mix[616,759,991, etc.]

Weighted direction score: 10 (Mixed / Neutral)

Benefit

Evidence Quality Summary[1560,1762,1794, etc.]

High when >=2 human meta-analyses, or >=5 human RCTs with substantial human literature volume.

Animal-only studies

503

In vitro / tissue

317

Total indexed

221

Safety adverse signals

131

Interaction signals

Human studies

Randomized trials

Meta-analyses

Study Type Breakdown

Distribution of evidence by study design strength

Randomized TrialsLevel 1b9

Human Studies (other)Level 3-471

All IndexedAll levels221

Evidence Strength: High

Composite of study volume, RCTs, and meta-analyses

Top Human Studies[1560,1762,1794, etc.]

PMID 17907228 • 2007 Oct 15

Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial.

Arthritis Rheum

Open PubMed

PMID 38800991 • 2024 Jul 28

Ganoderma lucidum dry extract supplementation modulates T lymphocyte function in older women.

Br J Nutr

Open PubMed

PMID 39241163 • 2024

Efficacy of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Supplementation on Psychological Stress and Selective Fitness Profile Parameters in Female College Students in West Bengal, India.

Community Report Frequency[616,759,991, etc.]

Benefit reports: 2

Adverse reports: 1

No-effect reports: 1

Mixed reports: 0

Unclear reports: 0

Signal confidence: 0.00

Top Reported Effects[616,759,991, etc.]

Benefits

Immune system modulation: 1
Sleep quality improvement: 1
Stress reduction: 1
Anti-inflammatory: 1
May support liver health: 1
Allergy symptom reduction: 1

Adverse

Autoimmune diseases without guidance: 1
Pre-surgery: 1
Mushroom allergy: 1

No Effect

no noticeable effect: 1

Insufficient empirical signal for a directional adjustment.

Reddit evidence: 0 mentions (confidence 0.00).

Amazon signal: 1 products scanned (948 ratings) (confidence 0.79).

Community Evidence Examples[616,759,991, etc.]

aggregate • benefit

Aggregate community signal: 4 directional mentions (benefit 2, adverse 1, no-effect 1, mixed 0).

Open mention

Retail Signal Examples

amazon

FlavCity Chocolate Protein Powder, Organic Cocoa with Collagen Peptides, Reishi & Cordyceps Mushrooms - Focus, Skin, Hair & Joint Support - 100% Grass Fed Whey All in One Smoothie, 20 Servings

Rating: 4.2 | Reviews: 948

Open product

Primary Source Links

Evidence Sources

Scientific Evidence Notes[1560,1762,1794, etc.]

1. PubMed evidence summary: Reishi

PUBMED • Humans + preclinical triage

Counts aggregated from automated literature sweep and tiering rules.

Outcome: Tier HIGH; humans 80, RCTs 9, meta-analyses 0.[1560,1762,1794, etc.]

Open source

2. Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial.

PUBMED • 2007 • Human evidence curation set

PMID 17907228 from Arthritis Rheum.

Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]

Implementation Blueprint

At-A-Glance Evidence Architecture[1560,1762,1794, etc.]

Evidence Tracking

Evidence Tracking

Top Signal Metrics[1560,1762,1794, etc.]

Community Direction Mix[616,759,991, etc.]

Evidence Quality Summary[1560,1762,1794, etc.]

Study Type Breakdown

Top Human Studies[1560,1762,1794, etc.]

Community Report Frequency[616,759,991, etc.]

Top Reported Effects[616,759,991, etc.]

Community Evidence Examples[616,759,991, etc.]

Retail Signal Examples

Primary Source Links

Scientific Evidence Notes[1560,1762,1794, etc.]

Safety and Pitfalls